We are fortunate to have access to high quality probiotic farms. Tests have confirmed that DNA-Shift 50 comes out with a high (more than 50 billion) CFU count when it leaves the manufacturing plant. This amount of CFU's is confirmed and guaranteed to still be alive 2 years from date of manufacture without the need of refrigeration. Kindly consider doing your own live bacteria test as done on https://www.amazon.com/review/RLGKU1LI919JN/ref=cm_cr_rdp_perm?ie=UTF8&ASIN=B01GKE4SFM
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